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ChemInform Abstract: Design and Synthesis of (E)-1-(3-Ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl-4-substituted Benzenes from 1-(2,6,6-Trimethylcyclohex-1-enyl)ethanol.

✍ Scribed by Bhaskar C. Das; Sakkarapalayam M. Mahalingam; Todd Evans; George W. Kabalka; J. Anguiano; K. Hema


Publisher
John Wiley and Sons
Year
2009
Weight
21 KB
Volume
40
Category
Article
ISSN
0931-7597

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## Abstract The title compound 4‐(N‐acetylamino) phenyl‐1‐[^14^C] retinoate (3) was synthesized by a 2‐step sequence. Carboxyl‐[^14^C] vitamin A (1) was treated with ethylchloroformate to form the mixed anhydride (2). Treatment with acetamidophenol and heating with a catalytical amount of 4‐dimethy