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ChemInform Abstract: Design and Synthesis of Constrained Epothilone Analogues: The Efficient Synthesis of Eleven-Membered Rings by Olefin Metathesis.

✍ Scribed by Jeffrey D. Winkler; Joanne M. Holland; Jiri Kasparec; Paul H. Axelsen


Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
30
Category
Article
ISSN
0931-7597

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Total Synthesis of Epothilone A: The Olefin Metathesis Approach. -Starting with the three building blocks (I)-(III) the coupling product (IV) is obtained. It is used for olefin metathesis as the key step in the synthesis of the title compound (VI). -(YANG, Z.;

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