While sesquiterpene illudins M and S (1 and 2, respectively) are highly cytotoxic compounds isolated from Omphalotus illudens, a semisynthetic derivative, (Γ)-irofulven (4; hydroxymethyl acylfulvene (HMAF)), has recently demonstrated far superior efficacy as an antitumor agent. [1, 2] (Γ)-Irofulven
β¦ LIBER β¦
ChemInform Abstract: Design and Synthesis of Antitumor Acylfulvenes.
β Scribed by T. C. MCMORRIS; J. YU; Y. HU; L. A. ESTES; M. J. KELNER
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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