ChemInform Abstract: Design and Preparation of Aza-Analogues of Benzo[c]phenanthridine Framework with Cytotoxic and Antiplasmodial Activities.
β Scribed by Ange-Desire Yapi; Nicolas Desbois; Jean-Michel Chezal; Olivier Chavignon; Jean-Claude Teulade; Alexis Valentin; Yves Blache
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The azaβMichael reaction of 10Ξ±β and 10Ξ²βdihydroartemisinin acrylates, respectively with amines and chloroquinoline amines gives access to novel artemisinin analogues (I) and (II) whose antiplasmodial and antitumor activity is evaluated.
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