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ChemInform Abstract: Copper-Catalyzed Synthesis of Highly Substituted Pyrrole and Isoindole Derivatives.

✍ Scribed by Sukla Nandi; Jayanta K. Ray


Publisher
John Wiley and Sons
Year
2012
Weight
13 KB
Volume
43
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The procedure is especially of interest for the preparation of natural products which consist of quinones bearing annellated N‐heterocycles.


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Formation of Highly Substituted Pyrrole Derivatives: An Unexpected Domino Reaction. -If the reaction is performed with 13 C methyl labeled amine (Ia), the carbon atom is found in the benzyl-substituted 3-position of pyrrole (IIIa). On the basis of this result a mechanism is proposed for the reaction