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ChemInform Abstract: Copper-Catalyzed Asymmetric Allylic Substitution with Aryl and Ethyl Grignard Reagents.

✍ Scribed by Khalid B. Selim; Ken-ichi Yamada; Kiyoshi Tomioka


Publisher
John Wiley and Sons
Year
2009
Weight
33 KB
Volume
40
Category
Article
ISSN
0931-7597

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## Abstract The __ortho__‐diphenylphosphanylbenzoyl (__o__‐DPPB) group was explored as a directing leaving group in copper‐mediated and copper‐catalyzed allylic substitution with Grignard reagents. Complete control of chemo‐, regio‐ and stereoselectivity with complete __syn__‐1,3‐chirality transfer