## Abstract High diastereo‐ and enantioselectivities are observed in the three‐component Mannich‐type reaction of diazoacetophenone (I) with alcohol (III) and para‐ or meta‐substituted aromatic imines (II) using a Rh~2~(O‐Ac)~4~/BINOL‐derived chiral phosphoric acid catalyst combination.
✦ LIBER ✦
ChemInform Abstract: Cooperative, Highly Enantioselective Phosphinothiourea Catalysis of Imine—Allene [3 + 2] Cycloadditions.
✍ Scribed by Yuan-Qing Fang; Eric N. Jacobsen
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 47 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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