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ChemInform Abstract: Convenient Synthesis of 1,6,7,8-Substituted 2-(3′,4′-Substituted-phenyl)-4-quinolones via a 4-Ethoxyflavylium Salt.

✍ Scribed by Shingo Sato; Takeshi Watanabe; Hironobu Kumagai; Nobuo Kitamura; Shigeru Matsuba; Toshihiro Kumazawa; Jun-ichi Onodera; Masanobu Suzuki

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
31
Category
Article
ISSN
0931-7597

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Synthesis and Pharmacological Activity of 2-(Substituted Phenyl)-3-(2 or 3-((4-Substituted Phenyl-4-hydroxy)piperidino)ethyl or propyl)-1,3-thiazolidin-4-ones. -A new series of 1,3-thiazolidinone analogues of loperamide (cf. (IV), 10 examples) are synthesized and evaluated for their antidiarrheal a