Controlling substitution patterns on the
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William T. Monte; William A. Kleschick; Jon Bordner
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Article
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1999
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Journal of Heterocyclic Chemistry
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English
β 445 KB
A highly effective method for the selective removal of chlorine from the 7-position of the 1,2,4-triazolo[1,5-a]pyrimidine ring in the presence of chlorine at the 5 - or 6 -positions is reported. The method involves treatment of the appropriate substrate with zinc-copper couple in the presence of ac