ChemInform Abstract: Construction of 1,2,5-Tricarbonyl Compounds Using Methyl Cyanoacetate as a Glyoxylate Anion Synthon Combined with Copper(I) Iodide-Catalyzed Aerobic Oxidation.

Construction of 1,2,5-Tricarbonyl Compou

Construction of 1,2,5-Tricarbonyl Compounds using Methyl Cyanoacetate as a Glyoxylate Anion Synthon Combined with Copper(I) Iodide-Catalyzed Aerobic Oxidation

✍ Se Hee Kim; Ko Hoon Kim; Jae Nyoung Kim 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB 👁 2 views

## Abstract A practical and efficient synthesis of various 1,2,5‐tricarbonyl compounds is described. The synthesis has been carried out by a conjugate addition of methyl cyanoacetate to the β‐position of α,β‐unsaturated carbonyl compounds and a subsequent copper(I) iodide‐catalyzed aerobic oxidatio