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ChemInform Abstract: Conformationally Restricted Analogues of Tryptophan: Synthesis of Chiral 3-Amino-4-indolyl-2-piperidones.

✍ Scribed by R. RODRIGUEZ; I. VINETS; A. DIEZ; M. RUBIRALTA; E. GIRALT


Book ID
112039267
Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
27
Category
Article
ISSN
0931-7597

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Conformationally restricted analogues of
✍ Ricardo RodrΓ­guez; M. Angels Estiarte; Anna Diez; Mario Rubiralta; Anna Colell; πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 French βš– 569 KB

~ ( otR, 3RS, 5S)-3-Amino-N-(2-hydroxy-1-phenylethyl)-5-methylthio-2piperidones 1 have been synthesized from enamide 2 by subsequent free radical addition of methanothiol on position 5 and amination of 3-position.