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ChemInform Abstract: Conformational Analysis of Some 5-Substituted 5H-Dibenzo[a,d]cycloheptenes.

โœ Scribed by Anders Hjelmencrantz; Annika Friberg; Ulf Berg

Publisher
John Wiley and Sons
Year
2000
Weight
27 KB
Volume
31
Category
Article
ISSN
0931-7597

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Bromine-Promoted Cyclization of an Olefinic ฮฑ-Aminonitrile: A Practical Synthesis of 5-Aminocarbonyl-10,11-dihydro-5H-dibenzo(a,d) cyclohepten-5,10-imine (ADCI). -ADCI (VII) is a selective, lowaffinity noncompetitive antagonist of the NMDA receptor showing promising anticonvulsant activity. In the