ChemInform Abstract: Chirospecific Synthesis of 1,4-Dideoxy-1,4-imino-D-arabinitol and 1,4-Dideoxy-1,4-imino-L-xylitol via One-Pot Cyclization.
β Scribed by J. H. KIM; M. S. YANG; W. S. LEE; K. H. PARK
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
The protected compounds (V) and (IX) are treated with iodine in MeOH to give pyrrolidines (VI) and (X), respectively. Iodine is found to be an efficient catalyst for deprotection of several O-and N-protecting groups. -(KIM, J.
π SIMILAR VOLUMES
Deoxymannojirimycin (1,5-dideoxy-1 ,S-imino-~-mannitol) 8, 1 -deoxynojirimycin (1,5-dideoxy-I ,5-iminO-D-ghcitol) 9, and 1,4-dideoxy-1,4-imino-~-arabinitol 10 are very effective glycosidase inhibitors."," The piperidine derivatives 8 and 9 have been known for some time,"] whereas the pyrrolidine der
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