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ChemInform Abstract: A Flexible and Efficient Synthesis of the Pyrrolidine α-Glycosidase Inhibitor 1,4-Dideoxy-1,4-imino-D-arabinitol (DAB-1).

✍ Scribed by Alison N. Hulme; Charles H. Montgomery; David K. Henderson

Publisher
John Wiley and Sons
Year
2000
Weight
34 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chirospecific Synth
ChemInform Abstract: Chirospecific Synthesis of 1,4-Dideoxy-1,4-imino-D-arabinitol and 1,4-Dideoxy-1,4-imino-L-xylitol via One-Pot Cyclization.
✍ J. H. KIM; M. S. YANG; W. S. LEE; K. H. PARK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

The protected compounds (V) and (IX) are treated with iodine in MeOH to give pyrrolidines (VI) and (X), respectively. Iodine is found to be an efficient catalyst for deprotection of several O-and N-protecting groups. -(KIM, J.