ChemInform Abstract: Chemoenzymatic Synthesis of the Morphine Skeleton via Radical Cyclization and a C10-C11 Closure.
β Scribed by G. BUTORA; T. HUDLICKY; S. P. FEARNLEY; A. G. GUM; M. R. STABILE; K. ABBOUD
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
Synthesis Toward Epothilone A: Coupling Reaction Between the Sulfone of C 1 -C 10 and the Allylic Bromide of C 11 -C 21 . -The synthesis of macrolide (XII), a precursor of epothilone A, involving the coupling between allylic bromide (IX) and sulfone (X) as the key step is reported. -