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ChemInform Abstract: Catalytic Asymmetric Dihydroxylation of Enamides and Application to the Total Synthesis of (+)-Tanikolide.

โœ Scribed by Benoit Gourdet; Hon Wai Lam

Publisher
John Wiley and Sons
Year
2011
Weight
35 KB
Volume
42
Category
Article
ISSN
0931-7597

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Catalytic Asymmetric Dihydroxylation of
Catalytic Asymmetric Dihydroxylation of Enamides and Application to the Total Synthesis of (+)-Tanikolide
โœ Benoit Gourdet; Dr. Hon Wai Lam ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 341 KB ๐Ÿ‘ 2 views

Asymmetric transformations of 1,1-disubstituted alkenes provide important building blocks for chemical synthesis, but are often plagued with low stereoselectivities because it can be difficult for a chiral reagent or catalyst to discriminate between the enantiotopic faces of these substrates. [1] Am