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Catalytic Asymmetric Dihydroxylation of Enamides and Application to the Total Synthesis of (+)-Tanikolide

✍ Scribed by Benoit Gourdet; Dr. Hon Wai Lam


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
376 KB
Volume
49
Category
Article
ISSN
0044-8249

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Catalytic Asymmetric Dihydroxylation of
✍ Benoit Gourdet; Dr. Hon Wai Lam πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 341 KB

Asymmetric transformations of 1,1-disubstituted alkenes provide important building blocks for chemical synthesis, but are often plagued with low stereoselectivities because it can be difficult for a chiral reagent or catalyst to discriminate between the enantiotopic faces of these substrates. [1] Am