Title compounds of type (VI) and (IX) are prepared and found to have good carbonic anhydrase isozymes I, II, and IV activating properties. Compared to histamine the higher activity of the compounds can be explained by introduction of the alkyl-or arylsulfonyl moiety.
ChemInform Abstract: Carbonic Anhydrase Activators. Part 21. Novel Activators of Isozymes I, II, and IV Incorporating Carboxamido and Ureido Histamine Moieties.
β Scribed by Andrea Scozzafava; Claudiu T. Supuran
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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