ChemInform Abstract: C3-Thia and C3-Carba Isosteres of a Carbocyclic Influenza Neuraminidase Inhibitor, (3R,4R,5S)-4-Acetamido-5-amino-3-propoxy-1- cyclohexene-1-carboxylic Acid.
β Scribed by W. LEW; M. A. WILLIAMS; D. B. MENDEL; P. A. ESCARPE; C. U. KIM
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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Synthesis and Biological Activity of Some 4-Amino-3-cinnoline Carboxylic Acid Derivatives. Part 4. 2,4-Dioxo-1,2,3,4tetrahydropyrimido[5,4-c]cinnolines. -A new series of the title compounds (III) are prepared by cyclocondensation of the corresponding cinnolinecarboxamides (I) with oxalyl chloride,