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ChemInform Abstract: C2-Functionalization of 1-Substituted Imidazoles with Aldehydes and Electron-Deficient Acetylenes: A Novel Three-Component Reaction.

✍ Scribed by Boris A. Trofimov; Ludmila V. Andriyankova; Kseniya V. Belyaeva; Anastasiya G. Mal'kina; Lina P. Nikitina; Andrei V. Afonin; Igor' A. Ushakov


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
41
Category
Article
ISSN
0931-7597

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C2-Functionalization of 1-Substituted Im
✍ Boris A. Trofimov; Ludmila V. Andriyankova; Kseniya V. Belyaeva; Anastasiya G. M πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 342 KB πŸ‘ 1 views

## Abstract A novel three‐component reaction between 1‐substituted imidazoles, aldehydes, and electron‐deficient acetylenes proceeds under mild conditions (20–25 Β°C, no catalyst, no solvent) to form an unknown family of C2‐functionalized imidazoles in up to 74 % yield, the function constituting a p