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ChemInform Abstract: Bisphosphonates Derived from Fatty Acids Are Potent Growth Inhibitors of Trypanosoma cruzi.

โœ Scribed by Sergio H. Szajnman; Brian N. Bailey; Roberto Docampo; Juan B. Rodriguez


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: New Potent Inhibito
โœ S. GIRAULT; S. BAILLET; D. HORVATH; V. LUCAS; E. DAVIOUD-CHARVET; A. TARTAR; C. ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 1 views

New Potent Inhibitors of Trypanothione Reductase from Trypanosoma cruzi in the 2-Aminodiphenylsulfide Series. -A series of compounds such as (I)-(III) are prepared to investigate their TR inhibition. Derivative (Ib) is revealed to be the best inhibitor described so far.