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ChemInform Abstract: Biosynthesis. Part 29. Colchicine: Studies on the Ring Expansion Step Focusing on the Fate of the Hydrogens at C-3 of Autumnaline.

โœ Scribed by R. N. WOODHOUSE; E. MCDONALD; R. RAMAGE; A. R. BATTERSBY

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
30
Category
Article
ISSN
0931-7597

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Stereochemical Variations on the Colchicine Motif. Part 3.The First Colchicine Analogues with an Eight-Membered B-Ring. Structure, Optical Resolution and Inhibition of Microtubule Assembly. -The desired title compound is prepared and investigated by X-ray crystal analysis. The enantiomeric resolutio