Synthetic Studies on Natural Products. Part 2. Two Efficient Methods for the Conversion of Camptothecin to Mappicine Ketone, an Antiviral Lead Compound. -The conversion of the naturally occurring alkaloid, camptothecin (I) to mappicine ketone (II) can be realized by treatment with BF 3 -etherate or
ChemInform Abstract: Biochemical Studies on Natural Products. Part 4. The First Conversion of Camptothecin to (S)-Mappicine by an Efficient Chemoenzymatic Method.
β Scribed by B. DAS; P. MADHUSUDHAN; A. KASHINATHAM
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Synthetic Studies on Natural Products. Part 9. Chemoenzymatic Transformation of the Natural Antitumor Alkaloid 20-O-Acetylcamptothecin to Mappicine Ketone and (S)-Mappicine. -The naturally occurring alkaloid (I) is converted to mappicine ketone (V), an antiviral lead compound, and its natural reduc