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ChemInform Abstract: Biginelli Reaction Starting Directly from Alcohols.

✍ Scribed by Garima Garima; Vishnu P. Srivastava; Lal Dhar S. Yadav


Publisher
John Wiley and Sons
Year
2011
Weight
28 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Biginelli Reaction Starting Directly from Alcohols. -The efficient one-pot proceeds via [hmim]HSO4-catalyzed oxidation of the alcohols with NaNO3 to aldehydes followed by cyclocondensation with urea and carbonyl compounds (14 examples). The methodology works well with aromatic alcohols, whereas aliphatic ones are unreactive.


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