ChemInform Abstract: Biginelli Reaction
β Scribed by Anil Saini; Sanjay Kumar; Jagir S. Sandhu
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 23 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable via the βReferencesβ option.
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## Abstract The threeβcomponent reaction which uses special heterocyclic aldehydes to give biopertinent hydropyrimidines opens a broad field of versatility (20 examples).
Biginelli Reaction Starting Directly from Alcohols. -The efficient one-pot proceeds via [hmim]HSO4-catalyzed oxidation of the alcohols with NaNO3 to aldehydes followed by cyclocondensation with urea and carbonyl compounds (14 examples). The methodology works well with aromatic alcohols, whereas alip