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ChemInform Abstract: Beta-Lactams Derived from the Reaction of Phenanthridines and 11H-Dibenzo[b,e]azepin-11-one with Phenylvaleryl Chloride. Synthesis of Fused Analogues of the Cholesterol Absorption Inhibitor Sch 48461.

✍ Scribed by A. AFONSO; S. B. ROSENBLUM; M. S. PUAR; A. T. MCPHAIL

Publisher: John Wiley and Sons
Year: 2010
Weight: 35 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199851282

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Beta-lactams derived from the reaction o

Beta-lactams derived from the reaction of phenanthridines and 11H-dibenzo[b,e]azepin-11-one with phenylvaleryl chloride. Synthesis of fused analogs of the cholesterol absorption inhibitor Sch 48461

✍ Adriano Afonso; Stuart B Rosenblum; Mohindar S Puar; Andrew T McPhail 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 230 KB

Phenanthridines 4 and the l lH-dibenzo[b,e]azepin-I l-one 17 were used as the imine components in the ketene-imine ]3-1actam synthesis to provide the fused tetracyclic [3-1actams 7, 8 and 18.