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ChemInform Abstract: Benzothiopyran-4-one Based Reversible Inhibitors of the Human Cytomegalovirus (HCMV) Protease.

✍ Scribed by Dashyant Dhanak; ET AL. ET AL.

Publisher: John Wiley and Sons
Year: 2010
Weight: 27 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199915158

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✦ Synopsis

Benzothiopyran-4-one Based Reversible Inhibitors of the Human Cytomegalovirus (HCMV) Protease.

-A new class of potent human cytomegalovirus protease inhibitors incorporating a benzothiopyranone nucleus (I) is developed. Kinetic data supporting a reversible mode of interaction for the representative sample (Id) are given. -(DHANAK, DASHYANT; ET

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