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ChemInform Abstract: Benzothiazines in Synthesis: A Route to Chiral Cyclobutanes.

โœ Scribed by Michael Harmata; Weijiang Ying; Xuechuan Hong; Charles L. Barnes


Publisher
John Wiley and Sons
Year
2008
Weight
49 KB
Volume
39
Category
Article
ISSN
0931-7597

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A Route to Chiral, Nonracemic Macroheterocycles. -Key step in the synthesis of the title compounds is the asymmetric alkylation of chiral tetrahydroisoquinoline formamidine (I). The structures of compounds (Vb) and (VIb), obtained by LiAlH 4 reduction of the corresponding amides, are investigated b