✦ LIBER ✦

ChemInform Abstract: A Route to Chiral, Nonracemic Macroheterocycles.

✍ Scribed by R. HUGHES; A. I. MEYERS

Publisher: John Wiley and Sons
Year: 2010
Weight: 33 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199846185

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✦ Synopsis

A Route to Chiral, Nonracemic Macroheterocycles.

-Key step in the synthesis of the title compounds is the asymmetric alkylation of chiral tetrahydroisoquinoline formamidine (I). The structures of compounds (Vb) and (VIb), obtained by LiAlH 4 reduction of the corresponding amides, are investigated by X-ray crystal structure analysis. -(HUGHES, R.; MEYERS,

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