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ChemInform Abstract: Asymmetric Total Synthesis of (+)-Carbocyclic Uracil Polyoxin C.

โœ Scribed by V. K. AGGARWAL; N. MONTEIRO


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Synthesi
โœ P. MERINO; S. FRANCO; F. L. MERCHAN; T. TEJERO ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB

Asymmetric Synthesis of an Isoxazolidine Nucleoside Analogue of Thymine Polyoxin C. -The first total synthesis of the isoxazolidine amino acid nucleoside analogue (VI) is based on the stereoselective nucleophilic addition of the silyl ketene acetal (II) to the enantiopure N-benzyl nitrone (I) as th