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ChemInform Abstract: Asymmetric Synthesis of (+)-Trachyspic Acid.

โœ Scribed by Kenji Morokuma; Yuko Taira; Yumiko Uehara; Setsuya Shibahara; Keisuke Takahashi; Jun Ishihara; Susumi Hatakeyama


Publisher
John Wiley and Sons
Year
2009
Weight
19 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Synthesi
โœ C. AGAMI; D. BIHAN; R. MORGENTIN; C. PUCHOT-KADOURI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB ๐Ÿ‘ 1 views

The synthesis of two enantiopure pipecolic acid esters (VI) and (XIII) is reported. Key steps are the intramolecular addition of allyl silane on an iminium double bond, generated via reaction of chiral ฮฒ-amino alcohols (I) and (VII), with glyoxal (II).