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ChemInform Abstract: Asymmetric Synthesis of the Roche Ester and Its Derivatives by Rhodium-INDOLPHOS-Catalyzed Hydrogenation.

✍ Scribed by Jeroen Wassenaar; Mark Kuil; Joost N. H. Reek


Publisher
John Wiley and Sons
Year
2008
Weight
41 KB
Volume
39
Category
Article
ISSN
0931-7597

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Asymmetric Synthesis of the Roche Ester
✍ Jeroen Wassenaar; Mark Kuil; Joost N. H. Reek 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB 👁 1 views

## Abstract (__S__)‐3‐Hydroxy‐2‐methylpropionate, known as the Roche ester, and several of its derivatives were successfully synthesized through asymmetric rhodium‐catalyzed hydrogenation, using INDOLPHOS (diisopropyl{1‐[(__S__)‐3,5‐dioxa‐4‐phosphacyclohepta[2,1‐__a__;3,4‐__a′__]dinaphthalen‐4‐yl]‐

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v