ChemInform Abstract: Asymmetric Synthesis of the Epoxide Portion of the Azinomycins.
β Scribed by H. J. BRYANT; C. Y. DARDONVILLE; T. J. HODGKINSON; M. SHIPMAN; A. M. Z. SLAWIN
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Asymmetric Synthesis of the Epoxide Portion of the Azinomycins.
-The short asymmetric synthesis of the title compound (VII) is based on the asymmetric dihydroxylation of benzyl 3,3-dimethylacrylate (I) by treatment with AD-mix-Ξ±. -(BRYANT, H. J.
π SIMILAR VOLUMES
Efficient Stereoselective Synthesis of the Epoxyacid Fragment of the Azinomycins. -Sharpless asymmetric epoxidation/kinetic resolution of the racemic alcohol (III), effectively available by three different routes, proceeds with the opposite sense of enantioselection than predicted using literature
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