Pseudourea-Mediated Dehydration of Tertiary and Benzylic Alcohols. -An efficient method for the dehydration of benzylic or tertiary alcohols is presented involving the copper-catalyzed formation of a pseudourea intermediate from alcohol and dicyclohexylcarbodiimide which undergoes subsequently elim
β¦ LIBER β¦
ChemInform Abstract: Asymmetric Synthesis of Tertiary Benzylic Alcohols.
β Scribed by Monika I. Antczak; Feng Cai; Joseph M. Ready
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 64 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
Vinyl, aryl, and alkynyl organometallics add to ketones containing a stereogenic sulfoxide to give tertiary alcohols in diastereoβ and enantiomerically pure form such as (III) or (VII).
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## Abstract Tertiary boronic esters smoothly undergo protodeboronation in the presence of CsF or TBAF in aqueous solution.