Asymmetric Total Synthesis of Stagonolid
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Dasari Ramesh; Singanaboina Rajaram; Peddikotla Prabhakar; Udugu Ramulu; Dorigon
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Article
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2011
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John Wiley and Sons
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German
β 159 KB
## Abstract A simple asymmetric total synthesis of stagonolide G (**1**) is described. Asymmetric dihydroxylation, regioselective epoxide ring opening, and vinyl __Grignard__ reactions are involved in generating the stereogenic centers C(4) and C(8), followed by __GrubbsβIIβ__catalyzed ringβclosing