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ChemInform Abstract: Asymmetric Synthesis of Stagonolide-D and Stagonolide-G.

✍ Scribed by Tridib Mahapatra; Tapas Das; Samik Nanda


Book ID
102065947
Publisher
John Wiley and Sons
Year
2011
Weight
53 KB
Volume
42
Category
Article
ISSN
0931-7597

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Asymmetric Total Synthesis of Stagonolid
✍ Dasari Ramesh; Singanaboina Rajaram; Peddikotla Prabhakar; Udugu Ramulu; Dorigon πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 German βš– 159 KB

## Abstract A simple asymmetric total synthesis of stagonolide G (**1**) is described. Asymmetric dihydroxylation, regioselective epoxide ring opening, and vinyl __Grignard__ reactions are involved in generating the stereogenic centers C(4) and C(8), followed by __Grubbs‐II‐__catalyzed ring‐closing