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ChemInform Abstract: Asymmetric Synthesis of Isoquinuclidine by Diels—Alder Reaction of 1,2-Dihydropyridine and Chiral Dienophile Utilizing a Chiral Lewis Acid.

✍ Scribed by Chigusa Seki; et al. et al.


Book ID
112044025
Publisher
John Wiley and Sons
Year
2012
Weight
35 KB
Volume
43
Category
Article
ISSN
0931-7597

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Asymmetric induction of four chiral cent
✍ Werbitzky, Oleg ;Klier, Konrad ;Felber, Helena 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 371 KB

## Abstract The Diels‐Alder reaction of __cis__‐5,6‐diacetoxy‐1,3‐cyclohexadiene (1), which has a __meso__ configuration, with the chiral nitroso dienophile 2 occurs with induction of four asymmetric centers in very high optical yield (ee = 94%) and leads to the dihydro oxazine 3 (89%). The influen