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ChemInform Abstract: Asymmetric Synthesis of Heptacosane-6,8-diols Induced by Chiral Sulfoxides.

โœ Scribed by Shigeyasu Motohashi; Ken Yasukawa; Michio Takido; Toshihiro Akihisa; Toru Takagi; Ryota Nishioka; Norio Tokutake


Publisher
John Wiley and Sons
Year
2001
Weight
28 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Synthesi
โœ W. OPPOLZER; O. FROELICH; C. WIAUX-ZAMAR; G. BERNARDINELLI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

The diastereomerically pure sulfinylating reagent (III) reacts with nucleophilic Grignard reagents or the zinc reagent derived from (VI) to yield chiral sulfoxides with excellent yields and enantioselectivities. Under specific conditions sequential reaction of (III) with LiN(Tms)2 followed by aldehy