Asymmetric synthesis of (2R,6R) and (2S,
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John W. Mickelson; E.Jon Jacobsen
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Article
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1995
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Elsevier Science
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English
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The title compounds were prepared via two efficient routes. The first sequence utilized a diastereospecific triflate alkylation in the key bond forming step while the second method relied on a novel intramolecular Mitsunobu reaction to set the required stereochemistry. Many pharmaceutical agents co