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ChemInform Abstract: Asymmetric Synthesis of 2H-Azirine Carboxylic Esters by an Alkaloid- Mediated Neber Reaction.

✍ Scribed by M. M. H. VERSTAPPEN; G. J. A. ARIAANS; B. ZWANENBURG


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Aziridine 2-Carboxy
✍ F. A. DAVIS; G. V. REDDY; C.-H. LIANG πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 2 views

Aziridine 2-Carboxylate Ester Mediated Asymmetric Synthesis of Ξ±-Alkyl Ξ²-Amino Acids. -Highly stereoselective reductive ring opening of the N-tosylaziridines (II) with LiAlH4 followed by oxidation of the syn-amino alcohols (III) provides an efficient entry to the asymmetric synthesis of Ξ±methyl Ξ²-am