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ChemInform Abstract: Asymmetric Synthesis of 1-Aryl-1,2,3,4-tetrahydroisoquinolines. Part 3. Investigation of the Diastereoselectivity During the Addition of an Enantiomerically Pure (2-Lithiophenyl)acetaldehyde Acetal to Various Imines.

✍ Scribed by B. WUENSCH; S. NERDINGER


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

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Diastereoselective Addition of Chiral (2
✍ Bernhard WΓΌnsch; Sven Nerdinger πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 354 KB πŸ‘ 1 views

A novel asymmetric synthesis of 1-aryl-1,2,3,4-tetrahy-sodium in liquid ammonia and ammonium cerium(IV) nitrate, respectively, to yield the primary amines 35 and 36. The acid-droisoquinolines has been developed. The key step in this synthesis is the diastereoselective addition of homochiral (2-catal