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ChemInform Abstract: Asymmetric PTC C-Alkylation Catalyzed by Chiral Derivatives of Tartaric Acid and Aminophenols. Synthesis of (R)- and (S)-α-Methyl Amino Acids.

✍ Scribed by Yuri N. Belokon; Konstantin A. Kochetkov; Tatiana D. Churkina; Nikolai S. Ikonnikov; Alexey A. Chesnokov; Oleg V. Larionov; Ishwar Singh; Virinder S. Parmar; Stepan Vyskocil; Henri B. Kagan


Publisher
John Wiley and Sons
Year
2001
Weight
35 KB
Volume
32
Category
Article
ISSN
0931-7597

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PTC and Organic Bases-LiCl Assisted Alkylation of Imidazolidinone-Glycine Iminic Derivatives for the Asymmetric Synthesis of α-Amino Acids. -A detailed investigation of the title reactions leads to imine (I) as the optimal substrate and A) as the optimal conditions for both yield and d.e. of the des