ChemInform Abstract: Asymmetric Propargylation of Ketones Using Allenylboronates Catalyzed by Chiral Biphenols.
β Scribed by David S. Barnett; Scott E. Schaus
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 42 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Prochiral aliphatic ketones as well as acetophenones and heterocyclic analogues are propargylated by trimethylsilylpropargyl boronate under optimized conditions to give the corresponding homopropargylic tertiary alcohols in general with <90% enantioselectivity.