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ChemInform Abstract: Asymmetric Pictet—Spengler Reactions: Synthesis of 1,2,3,4-Tetrahydroisoquinoline Carboxylic Acid (Tic) Chimeras

✍ Scribed by Jan Spengler; Hartmut Schedel; Joachim Sieler; Peter J. L. M. Quaedflieg; Quirinus B. Broxterman; Alexander L. L. Duchateau; Klaus Burger

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
32
Category
Article
ISSN
0931-7597

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Synthesis of 1,2,3,4-Tetrahydroisoquinol
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ChemInform Abstract: Pictet—Spengler Con
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Pictet-Spengler Condensation of N-Sulfonyl-β-phenethylamines with α-Chloro-α-phenylselenoesters. New Synthesis of 1,2,3,4-Tetrahydroisoquinoline-1-carboxylates. -Lewis acid promoted Pictet-Spengler type condensation of the tosylated β-phenethylamines (I) with α-chloro-α-seleno carboxylates (II) di