Asymmetric Michael addition of 2-nitropr
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PΓ©ter BakΓ³; LΓ‘szlΓ³ TΓΆke; Γron SzΓΆllΓΆsy; Petra Bombicz
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Article
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1997
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John Wiley and Sons
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English
β 173 KB
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Michael addition of 2-nitropropane 4 to a chalcone 3 catalyzed by crown ethers incorporating two glucose units (of 1 type) afforded the adduct 5 with an R-enantiomer excess (28% ee) while the aza-crown ethers containing one glucose unit (of 2 type) gave the same adduct favoring the S-enantiomer unde