ChemInform Abstract: Asymmetric Henry Reaction Catalyzed by a Zn-Amino Alcohol System.

✍ Scribed by Bing Zheng; Min Wang; Zhiyuan Li; Qinghua Bian; Jianyou Mao; Shuoning Li; Shangzhong Liu; Mingan Wang; Jiangchun Zhong; Hongchao Guo

• Publisher: John Wiley and Sons
• Year: 2012
• Weight: 41 KB
• Volume: 43
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201207021

✦ Synopsis

Abstract

Aromatic as well as aliphatic aldehydes undergo the Henry reaction with nitromethane under catalysis of an in situ generated chiral amino alcohol—Zn complex to give the corresponding β‐nitroalcohols in moderate to good enantioselectivity.