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ChemInform Abstract: An Unprecedented and Highly Chemoselective Esterification Method.

โœ Scribed by Adam Shih-Yuan Lee; Hui-Chun Yang; Feng-Yih Su


Publisher
John Wiley and Sons
Year
2001
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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An unprecedented and highly chemoselecti
โœ Adam Shih-Yuan Lee; Hui-Chun Yang; Feng-Yih Su ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 54 KB

A series of carboxylic acids was transformed to their corresponding methyl esters under CBr 4 /CH 3 OH (0.05 eq., 5 ml) reaction conditions. The rate of esterification is decreased with increasing bulkiness of the alcohol. Chemoselectivity can be achieved between phenylacetic and benzoic acids, sp 3