An unprecedented and highly chemoselecti
โ
Adam Shih-Yuan Lee; Hui-Chun Yang; Feng-Yih Su
๐
Article
๐
2001
๐
Elsevier Science
๐
French
โ 54 KB
A series of carboxylic acids was transformed to their corresponding methyl esters under CBr 4 /CH 3 OH (0.05 eq., 5 ml) reaction conditions. The rate of esterification is decreased with increasing bulkiness of the alcohol. Chemoselectivity can be achieved between phenylacetic and benzoic acids, sp 3