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ChemInform Abstract: An Organocatalytic [3 + 2] Cyclization Strategy for the Highly Enantioselective Synthesis of Spirooxindoles.

✍ Scribed by Arnaud Voituriez; Nathalie Pinto; Mathilde Neel; Pascal Retailleau; Angela Marinetti

Publisher
John Wiley and Sons
Year
2011
Weight
38 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

An Organocatalytic [3 + 2] Cyclization Strategy for the Highly Enantioselective Synthesis of Spirooxindoles. -Phosphine-promoted [3 + 2] annulation reactions between electron-poor allenes and 3-arylidene indolin-2-ones afford a new organocatalytic strategy for the synthesis of the spirocyclic core of oxindolic cyclopentanes with almost perfect stereochemical control. -(VOITURIEZ, A.;

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