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ChemInform Abstract: An Improved Synthesis of 1,2,3,4-Tetrahydroisoquinolines via Intramolecular Cyclization of N-Acyl-N-(aryl)methyl-2-(phenylsulfinyl) ethylamine by Pummerer Reaction.

✍ Scribed by T. SHINOHARA; J. TODA; T. SANO


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Novel Synthesis of
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Novel Synthesis of N-Methyl-1,2-benzosultams, an Unsuspected Demethylative Intramolecular Cyclization Reaction. -Treatment of 2-(dimethylamino)-and 2-aminobenzenesulfonic acids with POCl 3 /PCl 5 does not yield expected benzenesulfonyl chlorides but 1,2-benzosultams like (II) and (VI). The sultam r