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ChemInform Abstract: An Efficient Synthesis of Polysubstituted 1,3-Enynes from (E)-β-Iodovinyl Sulfones and Terminal Alkynes.

✍ Scribed by Xiao-Xia Gu; Mei-Hua Xie; Xin-Yang Zhao; Ying Sun; Wei Zhang; Fa-Dong Xie; Shao-Wu Wang


Publisher
John Wiley and Sons
Year
2009
Weight
35 KB
Volume
40
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Novel Two-Step Stereoselective Synthesis of (E)-Enamines and 1-Amino-1, 3-dienes from Terminal Alkynes. -The two-step synthesis of (E)-enamines and 1-amino-1,3-dienes is accomplished by regio-and stereoselective Ru-catalyzed addition of acetic acid to alkynes (I). The resulting acetates react with