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✦ LIBER ✦
ChemInform Abstract: An Efficient Chemical Method for Removing N-Terminal Extra Methionine from Recombinant Methionylated Human Growth Hormone.
✍ Scribed by O. NISHIMURA; M. SUENAGA; H. OHMAE; S. TSUJI; M. FUJINO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
An Efficient Chemical Method for Removing N-Terminal Extra Methionine from Recombinant Methionylated Human Growth Hormone.
-The title process is successfully achieved via a transamination reaction and a phenylene-1,2-diamine treatment. The method may be of more general use for the preparation of non-methionylated recombinant proteins for clinical use.
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