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ChemInform Abstract: An Efficient Chemical Method for Removing N-Terminal Extra Methionine from Recombinant Methionylated Human Growth Hormone.

✍ Scribed by O. NISHIMURA; M. SUENAGA; H. OHMAE; S. TSUJI; M. FUJINO


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


An Efficient Chemical Method for Removing N-Terminal Extra Methionine from Recombinant Methionylated Human Growth Hormone.

-The title process is successfully achieved via a transamination reaction and a phenylene-1,2-diamine treatment. The method may be of more general use for the preparation of non-methionylated recombinant proteins for clinical use.


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